Insulin resistance – what it is and how to address it

ngc development in lab

This article is intended for Indevex B2B partners and should not be regarded as information directed at consumers.

Insulin resistance is a term that has gained increasing attention as metabolism and blood sugar control have become central topics in health discussions. Insulin resistance occurs when the body’s cells no longer respond effectively to insulin, the hormone responsible for helping glucose enter the cells. When insulin does not function properly, blood glucose levels rise, forcing the body to produce even more insulin. Over time, this can lead to elevated blood sugar levels, metabolic dysfunction, and, in some cases, type 2 diabetes.

Research shows that insulin resistance often develops gradually and can persist for years without clear symptoms. At the same time, it is a condition that can be significantly influenced by changes in diet and lifestyle. For both consumers and brands, there is a growing need for evidence-based solutions that help prevent and stabilize glucose levels.

The link between blood sugar control and insulin sensitivity

Insulin sensitivity describes how effectively the body’s cells respond to insulin. High insulin sensitivity means that less insulin is required to transport glucose into the cells, a sign of good metabolic health. The opposite, low insulin sensitivity, leads to insulin resistance. When blood sugar levels fluctuate significantly over time, the pancreas is forced to release more insulin to maintain balance. Over time, this can disrupt glucose metabolism, weakening the cells’ ability to respond to insulin. Common signs of insulin resistance include

  • fatigue after meals
  • increased sugar cravings or hunger between meals
  • difficulty in keeping or losing body weight
  • high blood pressure
  • elevated blood glucose levels during health checkups.

Understanding the connection between blood sugar control and insulin sensitivity is therefore essential, both for individual health and for companies looking to develop products with genuine functional benefits.

How lifestyle and evidence-based ingredients can support metabolic health

Addressing insulin resistance requires long-term changes rather than short-term diets. When it comes to diet and insulin resistance, it is not about total restriction but about choosing the right types of carbohydrates and nutrients.

The role of diet

A diet designed to counter insulin resistance should focus on

  • fiber-rich foods that slow glucose absorption and stabilize blood sugar levels
  • whole grains and legumes that help maintain consistent energy
  • healthy fats and proteins that improve satiety and reduce insulin spikes.

Such a diet reduces the risk of major glucose fluctuations and supports the body’s natural insulin sensitivity.

The role of lifestyle

In addition to diet, physical activity and sleep play crucial roles. Exercise improves the muscles’ ability to absorb glucose, while lack of sleep and stress can increase the risk of insulin resistance. Even with healthy habits, maintaining stable glucose levels in modern life can be challenging. This is where innovative, clinically supported ingredients can make a measurable difference.

Scientific support – NGC®

Indevex has developed NGC®, a natural, clinically studied ingredient shown to influence glucose metabolism. By modulating digestion and nutrient absorption, NGC® can help promote steadier blood sugar curves and a more balanced insulin response.

NGC® is particularly well suited for products in functional nutrition, low-sugar diets, and dietary supplements aimed at improving metabolic health.

FAQ – Insulin resistance

How does blood sugar control affect insulin resistance?

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When blood sugar levels remain stable, the body needs to produce less insulin. This relieves the pancreas and helps maintain healthy insulin sensitivity.

Can insulin resistance be prevented or improved?

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Yes. Studies show that diet, physical activity, and weight management can improve insulin sensitivity and reduce the risk of insulin resistance.

What role does NGC® play in this context?

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NGC® is a clinically proven ingredient that supports glucose metabolism and helps smooth out blood sugar fluctuations. Over time, this can help improve the insulin response and reduce the risk of insulin resistance.

Why should brands focus on insulin resistance?

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Consumers are increasingly seeking products that prevent metabolic disorders rather than simply addressing symptoms. Developing products with documented effects on insulin sensitivity and blood sugar control enables brands to meet this demand and build credibility in a rapidly growing global market.

The content of this article was developed in consultation with Indevex’s scientific advisor.